At Hilton Head, Disney has a shuttle that runs to their beach house. The beach house is really nice. We also enjoy the activities at the resort. We like anything that B'lou Crabbe puts on - he plays about five musical instruments and is a story teller and magician from the low country. We went to his Ghost stories of the low country and had a ball.
The last time we were at Hilton Head, we did a day trip to Savannah - it was great. We did a trolley tour where we could just hop on and hop off at our leisure. WE also made a point to eat at Mrs. Wilkes Boarding house - the food was unbelievable. Probably 22 dishes of food on the table and everything was good - country cooking. They only serve until 2:00 Here's the website for Mrs. Wilkes:
http://www.mrswilkes.com/
For the ultimate, I'd love to get a 3 bedroom Hilton Head Grand Villa for our May 2010 trip. We stayed in one last November (was lucky enough to book one on a II exchange) and we loved it. It had a fireplace and 4 bathrooms in it. It was probably 2200 square feet easy.